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李春美,中共黨員,女,1973年生,77779193永利官网食品科技學院三級崗教授,博士,博士生導師。77779193永利官网食品科技學院教指委主任。獲得“教育部新世紀優秀人才”、“ 湖北省傑出青年基金”、獲得“77779193永利官网教學質量優秀一等獎””,“77779193永利官网研究生導師教書育人獎”,“77779193永利官网先進女教職工”等榮譽稱号;多次被評為77779193永利官网“優秀共産黨員”。
1991/09-1995/06:77779193永利官网食品科技學院食品科學專業,學士;1995/09-2000/06:77779193永利官网食品科技學院農産品加工及貯藏工程專業,博士。
2000/07-2002/12:77779193永利官网食品科技學院,講師;2003/01-2010/12:77779193永利官网食品科技學院,副教授;2009/05-2010/05:美國Miami University,訪問學者;2010/12-至今:77779193永利官网食品科技學院,教授/博導;2018/01-2018/03:美國羅格斯大學(Rutgers University),高級訪問學者。
一直緻力于植物多酚的研究,研究方向穩定。圍繞與植物多酚相關的農産品的采後加工難點,以富含多酚的柿子、茶等為對象,重點針對其加工與高值利用過程中關鍵性技術難點所涉及的化學結構、活性變化及機制等展開深入研究。主要研究方向有:1.植物多酚提取分離新技術,結構分析,健康調節作用及其分子機制。2. 特色果蔬以及林果精深加工及其高值高效利用新技術研究。3. 功能因子健康挖掘及健康産品開發。
(一)入選的人才計劃項目:1. 教育部新世紀優秀人支持計劃,NCET-12-0865,“柿子單甯對非酒精性脂肪肝脂質代謝影響機制研究”,2013.1-2015.12,50萬元,主持2. 湖北省傑出青年基金,2011CDA108 ,“柿子單甯與其特異靶标蛇毒磷脂酶A2的結合作用及機制”,2012.1-2013.12,10萬元,主持3. 武漢市青年科技晨光計劃,20065004116-24 ,“蓮藕色素前體物質與PPO超分子相互作用及其對蓮藕褐變的影響”,2006.1-2008.12, 4.5萬元,主持4. 瑞典國際科學基金(IFS),E/3657-1, “Study on the influence of oxidation of tea catechins on the flavor of green tea beverages during a long shelf life”IFS, 2004.1-2005.12,8000美元,主持。(二)主持的其它科研項目1. 國家自然科學基金面上項目“基于脂質筏互作精準解析膳食多酚調節脂質代謝的機制及構效關系”,32172201,58萬,主持,2022.1-2025.122. 湖北省重點研發項目“湖北特色漿果功能活性組分綠色制造關鍵技術研究”,2024BBB034,聯合申報,100萬,2024-20263. 國家重點研發計劃“特色經濟林優異種質發掘和精細評價”,2019YFD1000603-1,138萬,子課題主持,2019.5-2-2022.124. 國家重點研發計劃“特色經濟林采後果實與副産物增值加工關鍵技術研究”,2019YFD1002304,135萬,子課題主持,2020.1-2022.125. 2021年創新嘉興·精英引領“領軍人才”創業資助計劃C類“天然多元網絡抗氧化快速補充運動營養能量棒研發及産業化”,200萬元,2022.1-2024.12,主持6. 中央高校基本科研業務費專項資金“基于脂質筏結構破壞和IR結合的柿ECG二聚體抑制脂肪細胞分化的分子機制”,2018.1-2020.12, 24萬元,主持。7. 國家自然科學基金面上項目, 31571839 “柿稀有原花青素二聚體通過脂質筏及其上特異受體67LR抑制3T3-L1前脂肪細胞分化的分子機制”,81萬元,2016.1-2019.12,主持8. 國家自然科學基金面上項目,31271833 “DP9柿子單甯對其靶标蛋白蛇毒PLA2的特異識别及共價修飾位點研究”,2013.1-2016.12,80萬元,主持9. 公益性行業(農業)科研專項經費子課題, 201203047-01,“現代柿産業關鍵技術研究與試驗示範”,2013.1-2016.12,50萬元,主持10. 武漢市科技攻關項目,20130205010186,“柿子低溫噴霧幹燥新技術及系列産品開發”, 2013.1-2014.12,15萬元,主持11. 中央高校基本科研業務費專項資金“應季與反季節番茄主要營養、特征風味及代表性活性成分的環境調控研究”,2013-2015,40萬元,主持12. 國家“十二五”科技支撐計劃“南方特色果蔬食品加工關鍵技術研究”(子課題),2012-2015,10萬元,已結題,主持13. 中央高校基本科研業務費專項資金“柿單甯及其特征結構單元對其特異靶标蛇毒磷脂酶A2結構修飾機制”,2011PY119,2011-2013,15萬元,主持14. 國家自然科學基金面上項目,30972398,“柿子提取物解蛇毒關鍵級分的結構表征及作用機理研究”;2010.1-2012.12,30萬,主持15. 教育部科學技術研究重點項目,No.109115,“柿子單甯解蛇毒作用及其構效關系研究”, 2009.1-2011.12,10萬元,主持16. 湖北省重大科技攻關計劃,2007AA204A01,“淡水魚蛋白功能食品及廢棄物的高效利用技術研究”, 2007.1-2008.12,90萬元,主持
【近5年代表性論文】1. Mengyao Zhao, Yunfei Huang, Lin Zhu, Yajie Zhang, Yawei Xu, Yuhan Lu, Kaikai Li, and Chun-mei Li*. A moderately high-fat diet with proper nutrient quality improves glucose homeostasis, hinked to downregulation of intestinal CD36 mediated by the Loss of Desulfovibrio.J. Agric. Food Chem. 2024, 72, 22631−22644 (中科院SCI一區, IF 5.7) 2. Yunfei Huang, Wenqing He, Ruifeng Wang, Yangyang Jia, Lu Li, Yawei Xu, Yuhan Lu, Xiaoxiao Zhang, Feixue Wu, Chunmei Li*. A Simple Method for Preparing Chlorophyll Free Phenols from Olive Leaves and Efciently Enriching it in Refned Olive Oil. Food and Bioprocess Technology https://doi.org/10.1007/s11947-024-03514-w (中科院SCI二區)3. Yunfei Huang, Qingyun Guan, Zhuoya Zhang, Pengxiang Wang, Chunmei Li*. Oleacein: A comprehensive review of its extraction, puriffcation, absorption, metabolism, and health effects. Food Chemistry 433 (2024) 137334 (中科院SCI一區, IF8.5) 4. Pengxiang Wang, Zhuoya Zhang, Kaikai Li and Chunmei Li*.Rapid purification of alkylamides from Zanthoxylum bungeanum by medium-pressure liquid chromatography and the establishment of a numbness prediction model using an electronic tongue. Anal. Methods, 2024, 16, 1196–12055. Zhang yajie, Zhu Lin, Zhao Mengyao, Jia Yangyang, Li Kaikai, Li Chunmei.* The effects of inulin on solubilizing and improving anti-obesity activity of high polymerization persimmon tannin. International Journal of Biological Macromolecules. 2024:270,132232 (中科院SCI一區, IF 7.7) 6. Yangyang Jia, Meizhu Dang, Ibrahim Khalifa, Yajie Zhang, Yunfei Huang, Kaikai Li , Chunmei Li*. Persimmon tannin can enhance the emulsifying properties of persimmon pectin via promoting the network and forming a honeycomb-structure. Food Hydrocolloids 135 (2023) 108157 (中科院SCI一區, IF 11.504) 7.Jia Yangyang; Du Jing; Li Kaikai; Li Chunmei*, Emulsification mechanism of persimmon pectin with promising emulsification capability and stability. Food Hydrocolloids 2022, 131, 107727-107744. (中科院SCI一區, IF 11.504) 8. Hu Yuying; Julian McClements David; Wang Lufeng; Li Chunmei*, Formation and characterization of starch-based spherulite: Effect of molecular weight of potato amylose starch. Food chemistry 2022, 371, 131060. (中科院SCI一區, IF 9.231)9.Hu Yuying; Yu Ben; Wang Lufeng; JulianMcClements David*; Li Chunmei*, Study of dextrin addition on the formation and physicochemical properties of whey protein-stabilized emulsion: Effect of dextrin molecular dimension. Food Hydrocolloids 2022, 128, 107569-107582. (中科院SCI一區, IF11.504)10.Du Jing; Dang Meizhu; Jia Yangyang; Xu Yujuan; Li Chunmei*, Persimmon tannin unevenly changes the physical properties, morphology, subunits composition and cross-linking types of gliadin and glutenin. Food chemistry 2022, 387, 132913-132923. (中科院SCI一區, IF 9.231)11.Jia Yangyang.; Khalifa Ibrahim; Dang Meizhu; Zhang Yajie; Zhu Lin; Zhao Mengyao; Li Kaikai; Li Chunmei*, Confirmation and understanding the potential emulsifying characterization of persimmon pectin: From structural to diverse rheological aspects. Food Hydrocolloids 2022, 131, 107738-107756. (中科院SCI一區, IF 11.504)12. Li Xiaofang; Chen Haoze; JiaYangyang; Peng Jinming; Li Chunmei*. Inhibitory Effects against Alpha-Amylase of an Enriched Polyphenol Extract from Pericarp of Mangosteen (Garcinia mangostana). Foods, 2022, 11 (7), 1001-1018. (中科院SCI 二區, IF 5.561)13. Shen Qiruonan; Zhu Ting; Wu Caie; Xu Yujuan; Li Chunmei*, Ultrasonic-assisted extraction of zeaxanthin from Lycium barbarum L. with composite solvent containing ionic liquid: Experimental and theoretical research. Journal of Molecular Liquids 2022, 347, 118265-118276. (中科院SCI二區, IF 6.633)14.Wang Ruifeng; Zhu Wei; Dang Meizhu; Deng Xiangyi; Shi Xin; Zhang Yajie; Li Kaikai; Li Chunmei*, Targeting Lipid Rafts as a Rapid Screening Strategy for Potential Antiadipogenic Polyphenols along with the Structure–Activity Relationship and Mechanism Elucidation. Journal of Agricultural and Food Chemistry 2022, 70 (12), 3872-3885. (中科院SCI一區, IF 5.895)15. Zhu Ting; Shen Qiruonan; Xu Yujuan; Li Chunmei*, Ionic liquid and ultrasound-assisted extraction of chestnut shell pigment with good hair dyeing capability. Journal of Cleaner Production. 2022, 335, 130195-130205. (中科院SCI一區, IF11.027)16. Jinming Peng, Wenjun Wen, Ruifeng Wang, Kaikai Li, Gengsheng Xiao*, Chunmei Li*. The galloyl moiety enhances the inhibitory activity of polyphenols against the adipogenic differentiation in 3T3-L1 preadipocytes. Food & Function, 2022 : DOI: 10.1039/d1fo04179g (中科院SCI二區, IF6.317)17. Ruifeng Wang , Jinming Peng, Xin Shi, Sijia Cao, Yawei Xu , Gengsheng Xiao*, Chunmei Li*. Change in membrane fluidity induced by polyphenols is highly dependent on the position and number of galloyl groups. BBA - Biomembranes 1864 (2022) 184015(中科院SCI二區, IF4.019)18. Khalifa Ibrahim, Zhu Wei, Nawaz Asad, Li kaikai, Li Chunmei*. Microencapsulated mulberry anthocyanins promote the in vitro-digestibility of whey proteins in glycated energy-ball models. Food Chemistry, 2021, 345: 128805-128816. (中科院SCI一區, IF 7.514)19. Wang Ruifeng, Dang Meizhu, Zhu Wei, Li Chunmei*. Galloyl Group in B-type Proanthocyanidin Dimers Was Responsible for Its Differential Inhibitory Activity on 3T3-L1 Preadipocytes due to the Strong Lipid Raft-Perturbing Potency[J]. Journal of Agricultural and Food Chemistry, 2021, 69(17): 5216-5225. (中科院SCI一區, IF 5.279)20. Khalifa Ibrahim, Du Jing, Nawaz Asad, Li Chunmei*. Multiple co‐pigments of quercetin and chlorogenic acid blends intensify the color of mulberry anthocyanins: insights from hyperchromicity, kinetics, and molecular modeling investigations [J]. Journal of the Science of Food and Agriculture, 2021, 101(4):1579-1588. (中科院SCI二區, IF 3.638)21. Hu Yuying, Julian McClements David, Wang Lufeng, Li Chunmei*. Formation and characterization of starch-based spherulite: Effect of molecular weight of potato amylose starch. Food Chemistry. 2021, 371:131060-123069. (中科院SCI一區, IF 7.514)22. Ruifeng Wang, Ibrahim Khalifa, Xia Du, Kaikai Li, Yujuan Xu, Li Chunmei*. Effects of anthocyanins on beta-lactoglobulin glycoxidation: a study of mechanisms and structure-activity relationship. Food & Function. 2021,12(21):10550-10562 (中科院SCI二區, IF 5.396)23. Du Jing, Dang Meizhu, Khalifa Ibrahim, Du Xia, Xu Yujuan, Li Chunmei*. Persimmon tannin changes the properties and the morphology of wheat gluten by altering the cross-linking, and the secondary structure in a dose-dependent manner. Food Research International, 2020, 137:109536. (中科院SCI一區, IF 6.475)24. Khalifa Ibrahim, Zhu Wei, Mohammed Hammad Hamed Hammad, Dutta Kunal, Chunmei Li*. Tannins inhibit SARS‐CoV‐2 through binding with catalytic dyad residues of 3CLpro: An in silico approach with 19 structural different hydrolysable tannins. Journal of food biochemistry, 2020, 44(10): e13432. (中科院SCI三區, IF 2.720)25. Zhu Wei, Khalifa Ibrahim, Wang Ruifeng, Chunmei Li*. Persimmon highly galloylated‐tannins in vitro mitigated α‐amylase and α‐glucosidase via statically binding with their catalytic‐closed sides and altering their secondary structure elements. Journal of food biochemistry, 2020, 44(7): e13234. (中科院SCI三區, IF 2.720)26. Chen Jinyu, Du Jing, Li Mengli, Chunmei Li*. Degradation kinetics and pathways of red raspberry anthocyanins in model and juice systems and their correlation with color and antioxidant changes during storage. LWT-Food science and technology, 2020, 128:109448. (中科院SCI一區, IF 4.952)27. Khalifa Ibrahim, Xia Du, Dutta Kunal, Peng Jinming, Jia Yangyang, Chunmei Li*. Mulberry anthocyanins exert anti-AGEs effects by selectively trapping glyoxal and structural-dependently blocking the lysyl residues of β-lactoglobulins. Bioorganic chemistry, 2020, 96:103615. (中科院SCI二區, IF 5.275)28. Li Jin, Zeng Jian, Peng Jinming, Jia Yangyang, Chunmei Li*. Simultaneous determination of the pharmacokinetics of A-type EGCG and ECG dimers in mice plasma and its metabolites by UPLC-QTOF-MS. International journal of food sciences and nutrition, 2020, 71(2): 211-220. (中科院SCI三區, IF 3.833)29. Wang Ruifeng, Zhu Wei, Peng Jinming, Li Kaikai, Chunmei Li*. Lipid rafts as potential mechanistic targets underlying the pleiotropic actions of polyphenols. Critical Reviews in Food Science and Nutrition,2022,62:2, 311-324, DOI: 10.1080/10408398.2020.181517130. Wei Zhu, Ruifeng Wang, Khalifa, Ibrahim and Chunmei Li*, Understanding toward the Biophysical Interaction of Polymeric Proanthocyanidins (Persimmon Condensed Tannins) with Biomembranes: Relevance for Biological Effects,Journal of Agricultural and Food Chemistry, 2019,67,11044-11052(中科院SCI一區,IF 3.571)31. .Jing Du, Fen Yao, Mengying Zhang, Ibrahim Khalifa, Kaikai Li, and ChunMei Li*. Effect of persimmon tannin on the physicochemical properties of maize starch with different amylose/amylopectin ratios, International Journal of Biological Macromolecules, 2019,132:1193-1199(中科院SCI三區,IF 4.784)32. Jinming Peng, Kaikai Li, Wei Zhu, Rongzu Nie, Ruifeng Wang, and ChunMei Li*, Penta-O-galloyl-beta-D-glucose, a hydrolysable tannin from Radix Paeoniae Alba, inhibits adipogenesis and TNF-alpha-mediated inflammation in 3T3-L1 cells, Chemical biological interactions, 2019,302,156-163(中科院SCI三區,IF 3.407)33. Rongzu Nie, Meizhu Dang , Kaikai Li, Jinming Peng, Jing Du, Mengying Zhang, and ChunMei Li*, A-type EGCG dimer, a new proanthocyanidins dimer from persimmon fruits, interacts with the amino acid residues of A beta(40) which possessed high aggregation-propensity and strongly inhibits its amyloid fibrils formation,Journal of Functional Foods, 2019, 52, 492-504(中科院SCI二區,IF 3.197)
【專利】1. 李春美,萬瓊紅,熊善柏,鐘朝晖,黨美珠.從淡水魚魚鱗中制備未變性膠原蛋白的方法, ZL200810048018.32. 李春美; 楊立; 鄒波; 杜靜, 一種抗氧化補鈣魚鱗肽鈣複合咀嚼片及其制備方法, ZL201210010943.33. 李春美; 杜靜; 葛珍珍; 徐澤; 朱維,一種柿子全果低溫噴霧幹燥粉及其制備方法,ZL2014101900840.94. 李春美,吳思,李凱凱,鄧祥宜,彭進明. 一種柿子山楂果醬及其制備方法,ZL201710213858.X5. 李春美,沈齊若楠,朱婷. 一種提取枸杞中玉米黃素的方法和應用。ZL202110620722.76. 李春美,彭進明,劉滔,王冬林,徐澤.一種柿子全果果糕及制造方法與品質檢測,申請号:CN201410500301.07. 李春美,朱婷,沈齊若楠. 一種提取闆栗殼中闆栗色素的方法和在染發劑中的應用。ZL202110706697.48. 李春美; 王玥; 李凱凱; 楊明美; 鄧祥宜, 一種柿果乳酸菌發酵果汁飲料制備方法, 申請号:CN2017010601.3243909. 李春美,易蔔拉欣•哈裡發,賈洋洋,一種摻入微膠囊化桑葚多酚的能量球的制作方法,申請号:CN201811418181.410. 李春美,李凱凱,石鑫,張亞傑,王瑞豐,徐金帥,賈洋洋.一種柿子低聚原花青素的制備方法及其應用,申請号:CN202010019052.911. 李春美,王瑞豐,朱維,一種抗肥胖活性化合物的篩選方法,申請号:CN202010709429.312. 李春美,杜霞,李凱凱, 朱琳,一種具有抗糖功效的組合物及其應用,申請号:CN202010749801.313. 李春美,李凱凱,張亞傑,侯焘,李曉芳,陳平,餘穎.一種高聚原花青素的增溶方法及其制得的複合物和應用,申請号:CN202011464022.514. 李春美,賀婷.一種富含玉米黃素杏仁油的組合物及其應用,申請号:CN202110522818.X15. 李春美,李凱凱,劉渝.一種複合谷物堅果能量棒及其制作方法, 申請号:CN202110681717.7【科技獎勵和鑒定成果】1. 2021年,傳統果幹蜜餞現代化加工關鍵技術及産業化“,獲得中國輕工業聯合會科學技術進步獎一等獎(排名第4,編号2021-J-2-12)2. 2019年,“特色漿果的營養健康效應及其精深加工關鍵技術研究與應用”,獲廣東省科技進步一等獎(排名第3,3/15,編号J03-1-01-R03)3. 2019年,“亞熱帶特色水果高效加工及産業化”,獲中國産學研合作創新成果獎一等獎(排名第6,編号20199056)4. 2018年,“嶺南大宗水果綜合加工關鍵技術及産業化應用”,獲廣東省科技進步一等獎(排名第6,編号B03-1-01-R06)5. 2017年,獲中華人民共和國農業部科技進步二等獎(排名第6)6. 2017年,獲神農中華農業科技獎(排名第6)7. 李春美(6/24), 華南特色水果綜合加工關鍵技術及産業化, 中華人民共和國農業部, 科技進步, 省部二等獎, 2017.11.17(徐玉娟; 肖更生; 吳繼軍; 餘元善; 唐道邦; 李春美; 溫靖; 張岩; 陳衛東; 甯進輝;李興斌; 林羨; 陳于隴; 李俊; 黃盛鋒; 衛高利; 張友勝; 劉子放; 李升鋒; 劉學銘; 傅曼琴; 鄒波; 安可婧; 姚錫鎮)證書編号:KJ2017-R2-033-068. 李春美,杜靜,李凱凱. “柿果全粉高效制備關鍵技術研究”,通過湖北省科技廳組織的成果鑒定,鑒定結果:國際先進;2017.1
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